For He hath made Him to be sin for us, who knew no sin; that we might be made the righteousness of God in Him. – 2 Corinthians 5:21

If sin had been blotted out so readily, and nothing more said of it, what effect would that have had on us in the future? I think that everyone who has felt the burden of sin, and has stood at the foot of the cross, and heard the cries of the great Sacrifice, and read God’s wrath against sin written in crimson lines upon the blessed and perfect person of the innocent Savior-every such person feels that sin is an awful thing. You cannot trifle with transgression after a vision of Gethesmane. You cannot laugh at it, and talk about the littleness of its demerit, if you have once stood on Golgotha, and heard the cry, “Eli, Eli, lama sabachthani?” The death of the Son of God upon the cross is the grandest of all moral lessons, because it is a lesson that affects the very soul of the man and changes his whole idea of sin. The cross straightens him from the desperate twist which sin gave him at the first. The cure of the first Adam’s fall is the second Adam’s death-the second Adam’s grace, which comes to us through His great sacrifice. We love sin till we see that it killed our best Friend, and then we loathe it evermore. I say, again, that if the great Father did forgive you, and said, “There is nothing in it; go your way, it is all over;” you would have lacked that grandest source of sanctified life which now you find in the wounds of Him who has made sin detestable to you, and has made perfect obedience, even unto death, the subject of you soul’s admiration. Now you long to be unto the great Father, in your measure, what your great Redeemer was to Him when He magnified the law and made it honorable. This is no mean benefit. ~ C.H. Spurgeon

https://www.blueletterbible.org/comm/spurgeon_charles/sermons/2207.cfm

For He hath made Him to be sin for us, who knew no sin… – 2 Corinthians 5:21

God cannot look where there is sin with any pleasure, and though as far as Jesus is personally concerned, He is the Father’s beloved Son in whom He is well pleased; yet when He saw sin laid upon His Son, He made that Son cry, “My God! My God! why hast Thou forsaken Me?” It was not possible that Jesus should enjoy the light of His Father’s presence while He was made sin for us; consequently, He went through a horror of great darkness, the root and source of which was the withdrawing of the conscious enjoyment of His Father’s presence. More than that, not only was light withdrawn, but positive sorrow was inflicted…What were the pangs, which Christ endured? I cannot tell you. You have read the story of His crucifixion. Dear friends, that is only the shell, but the inward kernel who shall describe? I doubt not that the Godhead within gave a peculiar sensitiveness to the holiness of Christ’s nature, so that sin must have become even more abhorrent to Him than it would have been to a merely perfect man. His griefs are worthy to be described according to the Greek Liturgy as “unknown sufferings.” The height and depth, the length and breadth of what Jesus Christ endured no heart can guess, nor tongue can tell, nor can imagination frame; God only knows the griefs to which the Son of God was put when the Lord made to meet upon Him the iniquity of us all. To crown all there came death itself. Death is the punishment for sin…whatever over and beyond natural death was intended in the sentence, “In the day thou eatest thereof thou shalt surely die,” Christ felt. Death went through and through Him… “He became obedient to death, even to the death of the cross.” ~ C.H. Spurgeon

https://www.blueletterbible.org/Comm/spurgeon_charles/sermons/0694.cfm

…the LORD hath laid on Him the iniquity of us all. – Isaiah 53:6

It has been asked, Was it just that sin should thus be laid upon Christ? We believe it was rightly so, first because it was the act of Him who must do right, for “the Lord hath laid on Him the iniquity of us all.” Jehovah, He against whom the offense was committed, and who has ordained that the sin of the people spoken of should be laid upon Christ. To impugn this, then, would be to impugn the justice of Jehovah, and I pray that none of us may have the hardihood to do that. Shall the potsherd venture to strive with the potter? shall the thing formed contend with the Creator of all things? Jehovah did it; and we accept it as being right, caring not what men may think of Jehovah’s own deed. Remember, moreover, that Jesus Christ voluntarily took this sin upon Himself. It was not forced upon Him; He was not punished for the sins of others with whom He had no connection and against His will; but He His own self bare our sins in His own body on the tree, and while bearing it said, “No man taketh My life from Me, but I lay it down of Myself.” It was according to His own eternal agreement made with the Father on our behalf; it was according to His own expressed desire, for He had a baptism to be baptized with, and He was straitened until it was accomplished; and therefore whatever of injustice might be supposed, it is removed by the fact that He who was mainly concerned in it was Himself voluntarily placed in such a position. But I would have you remember, beloved, that there was a relationship between our Lord and His people, which is too often forgotten, but which rendered it natural that He should bear the sin of His people. Why does the text speak of our sinning like sheep? I think it is because it would call to our recollection that Christ is our Shepherd. It is not, my brethren, that Christ took upon Himself the sins of strangers. ~ C.H. Spurgeon

https://www.blueletterbible.org/Comm/spurgeon_charles/sermons/0694.cfm