And I will put enmity between…thy seed and her Seed; He shall bruise thy head, and thou shalt bruise His heel…. -Genesis 3:15

There was evidently to be in the world a Seed of the woman on God’s side against the serpent, and a seed of the serpent that should always be upon the evil side even as it is unto this day. The Church of God and the synagogue of Satan both exist. We see an Abel and a Cain, an Isaac and an Ishmael, a Jacob and an Esau; those that are born after the flesh, being the children of their father the devil, for his works they do, but those that are born again-being born after the Spirit, after the power of the life of Christ, are thus in Christ Jesus the Seed of the woman, and contend earnestly against the dragon and his seed. Here, too, the great fact of the sufferings of Christ is clearly foretold-“Thou shalt bruise His heel.” Within the compass of those words, we find the whole story of our Lord’s sorrows from Bethlehem to Calvary. “He shall bruise thy head”: there is the breaking of Satan’s regal power, there is the clearing away of sin, there is the destruction of death by resurrection, there is the leading of captivity captive in the ascension, there is the victory of truth in the world through the descent of the Spirit, and there is the latter-day glory in which Satan shall be bound, and there is, lastly, the casting of the evil one and all his followers into the lake of fire. The conflict and the conquest are both in the compass of these few fruitful words. They may not have been fully understood by those who first heard them, but to us they are now full of light. The text at first looks like a flint, hard and cold; but sparks fly from it plentifully, for hidden fires of infinite love and grace lie concealed within…Over this promise of a gracious God we ought to rejoice exceedingly. ~ C.H. Spurgeon

https://www.blueletterbible.org/Comm/spurgeon_charles/sermons/1326.cfm